Now We Are Six - The Hormone Surge of Middle Childhood - Natalie Angier via NYTimes.com

Middle childhood is where the social is put into the social animal:

Natalie Angier via NYTimes.com

In middle childhood, the brain is at its peak for learning, organized enough to attempt mastery yet still fluid, elastic, neuronally gymnastic. Children have lost the clumsiness of toddlerhood and can become physically gymnastic, too, and start practicing their fine motor skills. And because they are still smaller than adults, they can grow adept at a skill like, say, spear-tossing, without fear of threatening the resident men.

Middle childhood is the time to make sense and make friends. “This is the period when kids move out of the family context and into the neighborhood context,” Dr. Campbell said.

The all-important theory of mind arises: the awareness that other people have minds, plans and desires of their own. Children become obsessed with social groups and divide along gender lines, girls playing with girls, boys with boys. They have an avid appetite for learning the local social rules, whether of games, slang, style or behavior. They are keenly attuned to questions of fairness and justice and instantly notice those grabbing more than their share.

The mental and kinesthetic pliancy of middle childhood can be traced at least in part to adrenarche, researchers said, when signals from the pea-size pituitary at the base of the brain prod the adrenal glands to unleash their hormonal largess. Adrenal hormones like DHEA are potent antioxidants and neuroprotectants, Dr. Campbell said, and may well be critical to keeping neurons and their dendritic connections youthfully spry.

Evidence also suggests that the adrenal hormones divert glucose in the brain to foster the maturation of the insula and anterior cingulate cortex, brain regions vital to interpreting social and emotional cues.

In middle childhood, the brain is open for suggestions. What do I need to know? What do I want to know? Well, you could take up piano, chess or juggling, learn another language or how to ski. Or you could go outside and play with your friends. If you learn to play fair, friends will always be there.

Play nice, kids!